My main areas of interest include neuroscience and neuroimmunloogy. My research areas include the study of N-acetylaspartate and N-acetylaspartylglutamate, and the genetic disorder Canavan disease. Our laboratory has also investigated the kynurenine pathway to quinolinic acid synthesis in immune cells. We have also investigated the use of brief isoflurane administration for the treatment of organophosphate poisoning.
| Moffett JR. 2003. Reductions in N-acetylaspartylglutamate and the 67 kDa form of glutamic acid decarboxylase immunoreactivities in the visual system of albino and pigmented rats after optic nerve transections. JComp Neurol 458:221-239. |
| Moffett JR. 2010. Miasmas, germs, homeopathy and hormesis: Commentary on the relationship between homeopathy and hormesis. HumExpToxicol 29:539-543. |
| Moffett JR, Ariyannur PS, Arun P, Namboodiri MA. 2014. N-Acetylaspartate and N-Acetylaspartylglutamate in Central Nervous System Health and Disease. In: Stagg C, Rothman D, editors. Magnetic Resonance Spectroscopy: Tools for Neuroscience Research and Emerging Clinical Applications. San Diego, CA: Academic Press. p 71-90. |
| Moffett JR, Arun P, Ariyannur PS, Garbern JY, Jacobowitz DM, Namboodiri AM. 2011. Extensive aspartoacylase expression in the rat central nervous system. Glia 59:1414-1434. |
| Moffett JR, Arun P, Ariyannur PS, Namboodiri AM. 2013. N-Acetylaspartate reductions in brain injury: impact on post-injury neuroenergetics, lipid synthesis, and protein acetylation. Front Neuroenergetics 5:11. |
| Moffett JR, Arun P, Namboodiri MA. 2006a. Laboratory research in homeopathy: con. IntegrCancer Ther 5:333-342. |
| Moffett JR, Arun P, Puthillathu N, Vengilote R, Ives JA, Badawy AA, Namboodiri AM. 2020a. Quinolinate as a Marker for Kynurenine Metabolite Formation and the Unresolved Question of NAD(+) Synthesis During Inflammation and Infection. FrontImmunol 11:31. |
| Moffett JR, Blinder KL, Venkateshan CN, Namboodiri MA. 1998. Differential effects of kynurenine and tryptophan treatment on quinolinate immunoreactivity in rat lymphoid and non-lymphoid organs. Cell Tissue Res 293:525-534. |
| Moffett JR, Cassidy M, Namboodiri MA. 1989a. Selective distribution of N-acetylaspartylglutamate immunoreactivity in the extrapyramidal system of the rat. Brain Research 494:255-266. |
| Moffett JR, Els T, Espey MG, Walter SA, Streit WJ, Namboodiri MA. 1997. Quinolinate immunoreactivity in experimental rat brain tumors is present in macrophages but not in astrocytes. Experimental Neurology 144:287-301. |
| Moffett JR, Espey MG, Gaudet SJ, Namboodiri MA. 1993a. Antibodies to quinolinic acid reveal localization in select immune cells rather than neurons or astroglia. Brain Research 623:337-340. |
| Moffett JR, Espey MG, Namboodiri MA. 1994a. Antibodies to quinolinic acid and the determination of its cellular distribution within the rat immune system. Cell and Tissue Research 278:461-469. |
| Moffett JR, Espey MG, Saito K, Namboodiri MA. 1994b. Quinolinic acid immunoreactivity in cells within the choroid plexus, leptomeninges and brain vasculature of the immune stimulated gerbil. Journal of Neuroimmunology 54:69-73. |
| Moffett JR, Ives JA, Namboodiri AM. 2009. Fatty acids and lipids in neurobiology: A brief overview. In: Watson RR, editor. Fatty acids in health promotion and disease causation. Urbana, IL: AOCS Press. p 517-543. |
| Moffett JR, Namboodiri AM. 2006a. Preface: a brief review of N-acetylaspartate. In: Moffett JR, Tieman SB, Weinberger DR, Coyle JT, Namboodiri MA, editors. N-Acetylaspartate: A Unique Neuronal Molecule in the Central Nervous System. New York, NY: Springer Science + Business Media. p vii-xiii. |
| Moffett JR, Namboodiri MA. 1995. Differential distribution of N-acetylaspartylglutamate and N-acetylaspartate immunoreactivities in rat forebrain. Journal of Neurocytology 24:409-433. |
| Moffett JR, Namboodiri MA. 2003. Tryptophan and the immune response. ImmunolCell Biol 81:247-265. |
| Moffett JR, Namboodiri MA. 2006b. Expression of N -acetylaspartate and N -acetylaspartylglutamate in the nervous system. In: |
| Moffett JR, Tieman SB, Weinberger DR, Coyle JT, Namboodiri MA, editors. N -Acetylaspartate: A Unique Neuronal Molecule in the Central Nervous System. New York, NY: Springer Science + Business Media. p 7-26. |
| Moffett JR, Namboodiri MA, Cangro CB, Neale JH. 1991a. Immunohistochemical localization of N-acetylaspartate in rat brain. Neuroreport 2:131-134. |
| Moffett JR, Namboodiri MA, Ne |
Area of Research
Institution Affiliations
HJF research scientist in support of USU