My research interests lay in understanding the pathophysiology of extremity trauma and developing treatments for it. I've been working on developing a Prolong Care strategy of stabilizing a volumetric muscle loss injury (VML) with a delayed definitive care procedure.
I am also performing research on utilizing this VML treatment strategy as part of a multi-staged treatment strategy for a blast injury with a critical sized bone defect. By utilizing a multi-staged treatment strategy, we hope to mitigate the secondary adverse events of heterotopic ossification and multiple organ damage caused by extremity trauma.
| Clark AR, Kulwatno J, Kanovka SS, Klarmann GJ, Hernandez CE, Natoli RM, McKinley TO, Potter BK, Dearth CL, Goldman SM. A Two-Stage Approach Integrating Provisional Biomaterial-Mediated Stabilization Followed by a Definitive Treatment for Managing Volumetric Muscle Loss Injuries. J Funct Biomater. 2024 Jun 6;15(6):160. doi: 10.3390/jfb15060160 |
| Clark A, Kulwatno J, Kanovka SS, McKinley TO, Potter BK, Goldman SM, Dearth CL. “In situ forming biomaterials as muscle void fillers for the provisional treatment of volumetric muscle loss injuries.” Mater Today Bio. 2023 Sep 2;22:100781. doi: 10.1016/j.mtbio.2023.100781 |
| Clark A, Ghatak S, Guda PR, El Masry MS, Xuan Y, Sato AY, Bellido T, Sen CK. Myogenic tissue nanotransfection improves muscle torque recovery following volumetric muscle loss. NPJ Regen Med. 2022 Oct 20;7(1):63. doi: 10.1038/s41536-022-00259-y |
Area of Research
Institution Affiliations
HJF Assistant Professor, Department of Surgery, in support of Uniformed Services University